Several experimental and modeling studies in our lab seek to determine the synaptic and non-synaptic mechanisms leading to Coherent Neuronal Activity. Simply put, this type of activity results from the behavior of a collective of connected neurons – where the organized activity that emerges appears as “more than the sum of the parts”. Current research projects include the mechanisms and role of temporal encoding by neuronal populations as occurs during several behavioral and cognitive tasks (e.g. gamma oscillations). Complimentary research on the mechanisms of pathological (hyper) synchronization, as occurs during epileptic seizures, is necessary for the development of new therapeutic approaches that intelligently interfere with the specific pathology, rather then unspecifically disrupting brain function. This in turn requires a quantitative and systems approach to understanding and controlling brain function.

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