Neural Engineering Lab

Dr. Marom Bikson will present our paper on the effects of DBS electric field on blood-brain barrier permeability to the Columbia Brain Stimulation and Therapeutic Modulation journal club.  This will be relevant for other modalities like ECT, MST, and TMS.  See also the Neual Engineering Project Page,

Wednesday, 8/18/10 at 1pm in Pardes Room 5001.

Asif brings this popular press articles to our attention: PopSci and New Scientist articles.

This was with conventional tDCS. So imagine the the further "boost" with our HD-tDCS (abhi's key article, Soterix).

Soterix Medical is a CCNY Neural Engineering spin-off that will develop the most state-of-the-art technology for non-invasive neuromodulation including tDCS and HD-tDCS.

"Neural Engineering applies engineering principles to solve questions in brain research, interesting overview article" from the Neurotechnology twitter feed.

Davide Reato gives the first of three lectures today on neuron models. The first lecture introduces neuronal modeling to the uninitiated - first describing types of models (compartmental models, cascade models and black box models) then followed by a discussion on classes of spiking neurons. The second lecture in this series will dive into the ways to model neurons.

Xiang Zhou will present "Outer hair cell function correlates with tinnitus" at the Fourth International TRI Conference: Frontiers in Tinnitus Research in the University of Texas, Dallas (June 8-11).

Friday Lab meeting: Xiang Zhou presents his work on tinnitus modeling and psychophysics.

"We hypothesize that tinnitus is the result of a gain-adaptation mechanism that, when confronted with degraded peripheral input, increase neuronal gains such that spontaneous neuronal activity is perceived as a phantom sound. The aim of this study is to find a colleration between the tinnitus percept with measures of peripheral processing on an individual subject basis. We try to predict the tinnitus likeness spectrum from both distortation product otoacoustic emission(DPOAE) and audiogram with high frequency resolution." - Xiang Zhou

Congratulations to Preet Minhas et al. for a paper accepted to Journal of Neuroscience Methods!

"Electrodes for high-definition transcutaneous DC stimulation for applications in drug-delivery and electrotherapy, including tDCS" by Preet Minhas, Johnson Ho, Varun Bansal, Jinal Patel, Julian Diaz, Abhishek Datta, and Marom Bikson

Congratulations Abhi et al. on a paper accepted to NeuroImage!

“Transcranial Direct Current Stimulation in Patients with Skull Defects and Skull Plates: High-Resolution Computational FEM Study of Factors Altering Cortical Current Flow” by Abhishek Datta, Marom Bikson, and Felipe Fregni (collaborator at Harvard Medical).

Friday Lab Meeting: Jacek will present progress of the optimization of high-definition tDCS stimulation.

Ranu Jung, Associate Professor at the Center for Adpative Neural Systems in Arizona State University will give a seminar on "Neuromorphic Design and Neural Prosthesis for Restoring Sensorimotor Function.

Friday Lab Meetings: Davide will present his article on the effects of fields on gamma oscillations, "Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing – modulation, pacing and resonance"

Welcome Mathias Huber, from the Hamburg University of Applied Sciences, who is a visiting scholar in the Neural Engineering group.

Two technolgies developed at CCNY Neural Engineering featured at the NYC Emerging Medical Technologies Summit.

2:30 PM Special Friday Seminar: Dr. Mingzhou Ding (Professor BME at U, Florida) will speak on "Dynamic Organization of Brain Networks".

NOTE We will not have our regular Friday morning seminar on this day. Note the seminar is at 2:30 PM.

2:00 PM, Leslie Blaha (Indiana University, Bloomington) will present a special seminar on "A Dynamic Hebbian-style Model of Configural Learning"

Marom Bikson presented at the International Symposium on Neuromodulation in Sao Paulo, Brazil.

"In vitro studies: designing targeted stimulation protocols" work by Tom Radman, Asif Rahman, and Davide Reato. 

"Computer modeling : what have we learned to design new interventions?" work by Abhishek Datta.

Friday Lab Meetings: Asif Rahman presented recent data on effects of DC fields on cortical synaptic function.

The Medical University of South Carolina (MUSC) initates a clinical trial on experimental pain using our High-Definition transcranial Electrical Stimulation (HD-tES) system. Jeff Borckardt and Mark George will lead the trial.

Marom Bikson, Abhi Datta, and Varun Bansal visited MUSC to deliver and set-up the technology.

Tom's paper on Spike Timing Amplifies the Effect of Electric Fields on Neurons: Implications for Endogenous Field Effects (Thomas Radman, Yuzhuo Su, Je Hi An, Lucas C. Parra, and Marom Bikson. The Journal of Neuroscience, March 14, 2007) was featured and discussed on Scientific Blogging.

Two medical technolgies developed in our lab are selected for the upcomming "NYC MedTech" showcase, organized by Columbia University on March 26th.

Prasad Adusumilli will present "Real-time intraoperative detection of tissue hypoxia by a novel wireless Pulse Oximetry (WiPOX)" based on our hand-held sensor technology.

Marom Bikson will present "H-sink: A method to reduce tissue heating at implantable medical devices including neuroprosthetic devices" 

Friday Lab Meetings: João will present the experiments and preliminary results on visual perception using the synchronization of Eye tracking and EEG, and the motivations behind the experiments.

Friday Lab meetings: Xiang will present the experiments he is performing about the voltage measurements at the scalp applying extra-cranial AC electric fields.

Marom Bikson presents among the finalists of the NYC Bioaccelerate Prize.  "Breakthrough in Electrotherapy Technology: High-Density Transcranial Electrical Stimulation (HD-tES)". The presentation will be at the Bank of America Tower (One Bryant Park).

Maged completed his first PhD exam. Congratulations!

The new website is now available at neuralengr.com

NYC Bioaccelerate Award FINAL ROUND selects our High-Density Transcranial Electrical Stimulation therapy. Congratulations design team!

http://www.bioacceleratenyc.org

Marom Bikson speaks at the National Institute of Health, National Institute of Aging on "A new medical device for non-invasive neuro-modulation and therapy with very low-intensity electrical currents".

Marom Bikson speaks at the Creative Management of Childhood Epilepsy symposium at New York Presbyterian Hospital (brochure) on technical challenges in epilepsy detection and electrotherapy (slides).

Varun Bansal and Abhishek Datta attend and present at the CIMIT Innovation Congress 2009 in Boston (Varun's poster).

Asif presents his poster at the 2009 Society for Neuroscience (SfN 2009) conference in Chicago:

T. Radman, A. Rahman, A. Datta, D. Reato, M. Bikson, "Low-amplitude DC electric fields induce long-term potentiation in rat motor cortex in vitro"

Some pictures from Chicago:

                       

Two of our papers are published in Brain Stimulation. Congratulations to Abhi and team on another cover!

Radman T, Ramos RL, Brumberg JC, Bikson M. Role of cortical cell type and morphology in sub- and suprathreshold uniform electric field stimulation. Brain Stimulation. 2009; 2(4):215-228. PDF

Datta A, Bansal V, Diaz J, Patel J, Reato D, Bikson M. Gyri-precise head model of transcranial DC stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad. Brain Stimulation. 2009; 2(4):201-207. PDF

Marom Bikson presents insights on mechanisms and technology for tDCS at the National Institute of Health (NIH), National Institute of Neural Disorders and Stroke.  Slides

A picture from Davide’s birthday:



Congratulations to Yuzhuo Su who successfully defended her PhD thesis.

Cell reconstructions from Thomas Radmans upcoming paper "Role of Cortical Cell Type and Morphology in Sub- and Suprathreshold Uniform Electric Field Stimulation" posted on NeuroMorpho.Org.

Abhishek Datta gave his second PhD qualifying exam. Congratulations Abhi!

Davide gave a talk ("Effect of electric fields on gamma oscillations in brain slices") at the journal club of the Division of Brain Stimulation and Therapeutic Modulation at the Columbia University Medical Center.

The Journal of Medical Devices (Volume 3, Issue 2, June 2009) has published our following abstracts from the 2009 Medical Device Conference
 
1. High-Density Transcranial DC Stimulation (HD-tDCS): Targeting Software
A. Datta, V. Bansal, J. Diaz, J. Patel, L. Oliveira, D. Reato, and M. Bikson
J. Med. Devices 3, 027518 (2009)
 
2. High-Density Transcranial Direct Current Stimulation (HD-tDCS): Hardware Interface
J. Diaz, V. Bansal, A. Datta, J. Patel, and M. Bikson
J. Med. Devices 3, 027544 (2009)
 
3. High-Density Transcranial Direct Current Stimulation (HD-tDCS): Skin Safety and Comfort
J. Patel, V. Bansal, P. Minha, J. Ho, A. Datta, and M. Bikson
J. Med. Devices 3, 027533 (2009)
 
4. Temperature Control at DBS Electrodes Using Heat Sinks: Experimentally Validated FEM Model of DBS Lead Architecture
M. Elwassif, A. Datta, and M. Bikson
J. Med. Devices 3, 027534 (2009)
 
5. Intra-Operative Pulse Oximetry
L. Oliveira, E. Servais, N. Rizk, P. Adusumilli, and M. Bikson
J. Med. Devices 3, 027533 (2009)